Glucosinolates in Seeds of Arabis hirsuta (L.) Scop.: Some New, Naturally Derived Isothiocyanates.
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چکیده
منابع مشابه
Glucosinolates, isothiocyanates and indoles
Although isothiocyanate and indole compounds derived from cruciferous vegetables appear to be structurally unrelated, they are both derived from glucosinolates. These sulfur-containing glycosides are found in the order Capparales, which includes the large family Brassicaceae. The glucosinolate molecule comprises a common glucone moiety and a variable aglucone side-chain, derived from one of sev...
متن کاملChemoprotection against cancer by isothiocyanates and glucosinolates.
Introduction Organic isothiocyanates (R-N=C=S) and glucosinolates, their biosynthetic precursors in plants, are attracting increasing attention as chemical and dietary protectors against cancer. More than 20 natural and synthetic isothiocyanates and several glucosinolates have been shown to block chemical carcinogenesis in animal models (see reviews in [1,2]); moreover, these substances are wid...
متن کاملIn vitro antiproliferative activity of isothiocyanates and nitriles generated by myrosinase-mediated hydrolysis of glucosinolates from seeds of cruciferous vegetables.
A comparison of the effect of isothiocyanates and nitriles derived from some glucosinolates, namely, epi-progoitrin, sinalbin, glucotropaeolin, glucocheirolin, and glucoraphenin, on human erythroleukemic in vitro cultured cells was studied. Many studies have in fact evidenced that a consumption of vegetable containing glucosinolates could reduce the development of colorectal cancer. In the expe...
متن کاملProtection of humans by plant glucosinolates: efficiency of conversion of glucosinolates to isothiocyanates by the gastrointestinal microflora.
Plant-based diets rich in crucifers are effective in preventing cancer and other chronic diseases. Crucifers contain very high concentrations of glucosinolates (GS; β-thioglucoside-N-hydroxysulfates). Although not themselves protective, GS are converted by coexisting myrosinases to bitter isothiocyanates (ITC) which defend plants against predators. Coincidentally, ITC also induce mammalian gene...
متن کاملConversion of glucosinolates to isothiocyanates in humans after ingestion of cooked watercress.
Isothiocyanates (ITCs), major constituents of cruciferous vegetables, can inhibit tumorigenesis in rodents by modulating the metabolism of carcinogens. ITCs that occur as glucosinolates are released by myrosinase-mediated hydrolysis when raw vegetables are chopped or chewed. However, because cruciferous vegetables are commonly consumed by humans after being cooked, it is important to examine wh...
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ژورنال
عنوان ژورنال: Acta Chemica Scandinavica
سال: 1972
ISSN: 0904-213X
DOI: 10.3891/acta.chem.scand.26-0008